ANTIBACTERIAL ACTIVITY OF SINGLE AND MIXED AMMONIUM AND PHOSPHONIUM SALTS GRAFTED ON "GEL-TYPE" STYRENE-DIVINYLBENZENE COPOLYMERS* |
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| Authors: | Adriana POPA Corneliu-Mircea DAVIDESCU Smaranda ILIESCU Gheorghe ILIA Gheorghe DEHELEAN Lavinia MACARIE Radu TRIF Rumanian Academy |
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| Institution: | Adriana POPA1 Corneliu-Mircea DAVIDESCU2 Smaranda ILIESCU1 Gheorghe ILIA1 Gheorghe DEHELEAN1 Lavinia MACARIE1 Radu TRIF3 1 Rumanian Academy,Institute of Chemistry,24 M. Viteazul Str.,1900 Timisoara,Roumania. 2 "Politehnica" University,Faculty |
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| Abstract: | A systematic study on the synthesis and antibacterial activity of the quaternary "onium" salts grafted on an insoluble "gel-type" styrene-7% divinylbenzene copolymer by polymer-analogous reactions is showed. Antibacterial activity of quaternary ammonium and/or phosphonium salts grafted on polymer-supports has been studied against Staphylococcus aureus and Escherichia coli. A wide variety of "onium" salts bound to macromolecular supports with different quaternary groups and different quaternary chain length substituents were examined. The antibacterial activity of mixed "onium" salts increases as a consequence of the association of ammonium and phosphonium salts grafted on the same polymeric support. |
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| Keywords: | Antibacterial activity Staphylococcus aureus Escherichia coli Quaternary ammonium and/or phosphonium salts grafted on polymer-supports` |
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