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Synthesis of 3,4-dihydrobenzo[g]isoquinoline-1(2H)-ones and 3,4-dihydroisoquinoline-1(2H)-ones skeleton via intramolecular electrophilic cyclization |
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| Authors: | Min-Ruei Tsai |
| Institution: | Department of Chemistry, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, ROC |
| Abstract: | An original alternative approach to isoquinolines based on the installation of a benzene nucleus on a performed heterocyclic ring. Synthesis of 3,4-dihydrobenzog]isoquinoline-1(2H)-ones and 3,4-dihydroisoquinoline-1(2H)-ones via intramolecular electrophilic cyclization of 3,4-disubstituted lactams is reported. |
| Keywords: | Stepwise [3+3] annulation 3 4-Dihydrobenzo[g]isoquinoline-1(2H)-ones and 3 4-dihydroisoquinoline-1(2H)-ones Electrophilic cyclization |
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