Studies towards the total synthesis of contignasterol |
| |
Authors: | Irene Izzo Carmela Della Monica Francesco De Riccardis |
| |
Affiliation: | a Dipartimento di Chimica, University of Salerno, via S. Allende, Baronissi I-84081 (SA), Italy b Dipartimento di Scienze Farmaceutiche, University of Salerno, via Ponte Don Melillo, Fisciano I-84084 (SA), Italy |
| |
Abstract: | The (17R,20S,22S,24S) C20-C29 segment of contignasterol has been stereoselectively prepared in 8 steps and 40% overall yield from (S)-carvone. Synthetic studies towards contignasterol's C/D ring functionalization/isomerization are also reported. |
| |
Keywords: | Contignasterol Polyhydroxysteroids Marine metabolite anti-Inflammatory compounds Ene reactions |
本文献已被 ScienceDirect 等数据库收录! |
|