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A total synthesis of (+)-oxybiotin from d-arabinose |
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| Authors: | Velimir Popsavin Goran Benedekovi? Vladimir Divjakovi? |
| Affiliation: | a Department of Chemistry, Faculty of Sciences, University of Novi Sad, Trg D. Obradovi?a 3, 21000 Novi Sad, Serbia and Montenegro b Department of Physics, Faculty of Sciences, University of Novi Sad, Trg D. Obradovi?a 4, 21000 Novi Sad, Serbia and Montenegro c Laboratory for Chemical and Mineralogical Crystallography, Bern University, Freiestr. 3, CH-3012 Bern, Switzerland |
| Abstract: | A novel ten-step synthesis of (+)-oxybiotin, a biologically active analogue of (+)-biotin, has been achieved starting from d-arabinose. |
| Keywords: | 2,5-Anhydro sugars smallcaps" >d-Arabinose (+)-Oxybiotin Ring contraction Triphosgene Wittig reaction |
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