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Synthesis of new unsymmetrical polyarylester dendrimers |
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| Authors: | Srinagesh Kumar Potluri A Raghu Ramulu M Pardhasaradhi |
| Institution: | Gas Based Chemicals and Organic Intermediates Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
| Abstract: | Preparation of polyarylester dendrimers containing 2-(hydroxymethyl)-1,4-butanediol and 2,2-bis(hydroxymethyl)-1,4-butanediol cores is described. These polyarylester dendrimers are unsymmetrical with respect to chain lengths and function as model systems for studying in vitro controlled drug release systems. Reaction conditions for deprotection of trichloroethyl group of the dendritic wedges have been improved. |
| Keywords: | Dendrimers Convergent-divergent approach Dendritic wedge Unsymmetrical Polyaryl ester Trichloroethyl protection |
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