Synthesis of terminal disaccharide unit of Klebsiella pneumoniae ssp. R20 |
| |
Authors: | Mukund K Gurjar Arindam Talukdar |
| |
Institution: | National Chemical Laboratory, Pune 411 008, India |
| |
Abstract: | Synthesis of the terminal disaccharide unit of a novel α-(1→2) linked heptoglycan of K. pneumoniae ssp. strain R20 from methyl α-d-mannopyranoside has been presented. Central to the strategy is the application of Sharpless asymmetric dihydroxylation to introduce a new center at C-6 position of mannopyranoside. The coupling of two heptoglycans (12 and 13) was accomplished by a Lewis acid catalyst. |
| |
Keywords: | K pneumoniae manno-Heptopyranose Sharpless asymmetric dihydroxylation Glycosidation |
本文献已被 ScienceDirect 等数据库收录! |