|
|||||
|
|
The application of coulometry for total antioxidant capacity determination of human blood |
|
| Authors: | Ziyatdinova Guzel K Budnikov Herman C Pogorel'tzev Valery I Ganeev Talgat S |
| Institution: | a Department of Chemistry, Kazan State University, Kremlyevskaya, 18 Kazan, Russia b Department of internal diseases, Kazan State Medical University, Butlerova, 49 Kazan, Russia c Department of Hemodialysis, Center of an-of Kidney Organism Clearing, Ershova, 2 Kazan, Russia |
| Abstract: | New coulometric method for estimation of blood and plasma total antioxidant capacity (TAC) based on using electrogenerated bromine was proposed. TAC of blood from patients with chronic renal disease undergoing long-term hemodialysis was investigated. Statistical significant changes in TAC level of venous and arterial blood were found. Catalase activity and low density lipoproteins (LDL) concentrations were determined. Linear correlation between TAC and parameters mentioned was found. Contribution from some individual antioxidants was investigated. The developed method for TAC assay is expressive, simple, stable and reliable, and successfully could be used for TAC determination of some biological fluids. This method could be applied in clinic for estimation of blood TAC from patients. |
| Keywords: | Total antioxidant capacity Coulometric titration Chronic renal failure Blood Catalase Low density lipoproteins |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |