Luminescent oxide nanoparticles with enhanced optical properties |
| |
Authors: | Geneviève Mialon Melanie Poggi Thanh-Liem Nguyen Antigoni Alexandrou Jean-Pierre Boilot |
| |
Institution: | a Laboratory of Condensed Matter Physics, Ecole Polytechnique, Palaiseau 91128, France b Laboratory of Optics and Biosciences, Ecole Polytechnique, Palaiseau 91128, France |
| |
Abstract: | Yttrium vanadate particles doped with europium are studied for their applications as biomolecule labels. Two parts of our recent work are presented. The first concerns the thermal treatment of particles incorporated in a solid matrix. After annealing at 1000 °C and redispersion in water by dissolution of the matrix, the structural and optical properties are greatly improved without any modification of size; the obtained nanoparticles appear as perfect single crystals of 39 nm and have the same emission properties as the bulk material. Their quantum yield is worth 39% for 5% europium doping and the emission lifetime is 1 ms. The second aspect concerns the functionalization of the nanoparticles by the sol-gel condensation of aminopropyltriethoxysilane at the surface of particles. The chemical accessibility of amino groups grafted on the particles is measured by reaction with an organic fluorescent tag fluorescein isothiocyanate (FITC). These amine-coated nanoparticles were coupled to a peptidic toxin via a cross linker and allowed observation of the toxin motion bound to its membrane receptor. |
| |
Keywords: | Annealing Functionalization Protein tracking |
本文献已被 ScienceDirect 等数据库收录! |