| 环糊精在药物控制释放系统中的应用研究进展 |
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| 引用本文： | 黄怡,范晓东. 环糊精在药物控制释放系统中的应用研究进展[J]. 化学研究与应用, 2005, 17(6): 715-719 |
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| 作者姓名： | 黄怡 范晓东 |
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| 作者单位： | 咸阳师范学院化学系,陕西,咸阳,712000;西北工业大学理学院应化系,陕西,西安,710072 |
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| 基金项目： | 国家自然科学基金项目（20374040）资助;陕西省教育厅专项科研计划项目（05JK311）资助 |
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| 摘 要： | 因为环糊精的生物相容性和多功能性，通过改性以及各种剂型的设计，能够扩展其在医药领域的应用。本文介绍了环糊精及其衍生物在药物控制释放体系中的作用机理及特点，并结合本课题组的研究工作，综述了近年来环糊精在该领域中的应用研究进展。
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| 关 键 词： | 环糊精 药物载体 药物控制释放 |
| 文章编号： | 1004-1656（2005）06-0715-05 |
| 收稿时间： | 2005-01-04 |
| 修稿时间： | 2005-06-17 |
Progress in application of cyclodextrins and their derivatives as carriers for drug delivery system |
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| HUANG Yi,FAN Xiao-dong. Progress in application of cyclodextrins and their derivatives as carriers for drug delivery system[J]. Chemical Research and Application, 2005, 17(6): 715-719 |
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| Authors: | HUANG Yi FAN Xiao-dong |
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| Abstract: | Because of their bioadaptability and multi - functional characteristics, the application of cyclodxtrins in pharmaceutical field were extended by using of chemically modified cyclodextrins and design of various kinds of pharmaceutical formulations. The recent developments of application of cyclodextrins and their derivatives as carriers for drug delivery system were reviewed. The characteristics and mechanism of controlled release of cyclodentrins were also discussed. |
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| Keywords: | cyclodextrins carriers for drag delivery system controlled release |
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