Structure and biological activity of α-santonin chloro-derivatives |
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| Authors: | S. A. Ivasenko T. T. Edil’baeva A. T. Kulyyasov G. A. Atazhanova A. I. Drab K. M. Turdybekov V. A. Raldugin S. M. Adekenov |
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| Affiliation: | (1) Institute of Phytochemistry, Ministry of Education and Science of the Republic of Kazakhstan, Republic of Kazakhstan, 470032 Karaganda, ul. Gazalieva 4;(2) N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Division, Russian Academy of Sciences, 630090 Novosibirsk |
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| Abstract: | 2-Chloro-4,5α-epoxy-α-santonin and 2-chloro-α-santonin, the molecular structure of which was confirmed by an XSA, were produced by reacting α-santonin and chlorine in aqueous acetonitrile. It was found that 2-chloro-α-santonin is highly effective against trichomonas. __________ Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 30–33, January–February, 2006. |
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| Keywords: | sesquiterpene lactones α -santonin chlorination XSA NMR |
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