Nazarov Cyclization of Divinyl and Arylvinyl Epoxides: Application in the Synthesis of Resveratrol‐Based Natural Products |
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| Authors: | Dr Gangarajula Sudhakar Kovela Satish |
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| Institution: | Division of CPC (Organic Chemistry‐II), CSIR‐Indian Institute of Chemical Technology, Tarnaka, Hyderabad‐500007 (India) |
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| Abstract: | New variation in the Nazarov cyclization has been developed by preparing divinyl and arylvinyl epoxides as pentadienyl cation precursors for the first time. Highly substituted cyclopentadienes, hydrindienes, and indenes were synthesized to demonstrate the compatibility of this reaction with substrates bearing a variety of substitutions and having different types of epoxides. Application of this method in the synthesis of resveratrol‐based natural products was also demonstrated. |
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| Keywords: | cyclopentadienes dienyl epoxides pentadienyl cation natural products Nazarov cyclization |
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