New approach to the synthesis of 4-amino-2-pyridone and 1-phenyl-1,6-naphthyridinone derivatives based on substituted 3-and 5-formyl-2-pyridones |
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| Authors: | N. Z. Tugusheva L. M. Alekseeva A. S. Shashkov V. G. Granik |
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| Affiliation: | (1) State Research Center of Antibiotics, 3a ul. Nagatinskaya, 117105 Moscow, Russian Federation;(2) N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation |
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| Abstract: | The reactions of 3-cyano-3(5)-formyl-2-oxo-4-(phenylamino)-1,2-dihydropyridines with CH acids were studied. The previously unknown fused 2-pyridone derivatives containing the 4-aminopyridine fragment were synthesized by the Knoevenagel reaction. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1416-1420, August, 2006. |
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| Keywords: | 3-cyano-3(5)-formyl-2-oxo-4-(phenylamino)-1,2-dihydropyridines, 2,7-dioxo-1-phenyl-1,2,6,7-tetrahydro-1,6-naphthyridines, 2-imino-5(7)-oxo-1-phenyl-1,6-naphthyridi-nes Knoevenagel reaction NMR spectroscopy |
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