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Assessment of the therapeutic action of low-intensity laser radiation from the extent of local tissue saturation with oxygen
Authors:M. M. Asimov  R. M. Asimov  A. N. Rubinov  S. A. Mamilov  Yu. S. Plaksii
Affiliation:(1) B. I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, 68 prosp. Nezavisimosti, Minsk, 220072, Belarus;(2) PEUS-Testing, Gaggenau, Germany;(3) Institute of Applied Problems in Physics and Biophysics, National Academy of Sciences of Ukraine, Kiev
Abstract:We propose a method for dosimetry of the biological response to laser irradiation based on determination of the amount of oxygen additionally supplied to the tissue. We show that it is feasible to determine the therapeutic dose from the change in the degree of oxygen saturation of the blood, heart rate, hemoglobin concentration in the blood, and exposure time. __________ 13Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 73, No. 4, pp. 516–520, July–August, 2006.
Keywords:oxyhemoglobin  photodissociation  dosimetry  molecular oxygen  low-intensity laser radiation  laser medicine  phototherapy
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