Diversity-orientated synthesis of 3,5-bis(arylamino)pyrazoles |
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Authors: | Sé bastien DegorceFré dé ric H. Jung,Craig S. Harris,Patrice KozaJonathan Lecoq,Arnaud Stevenin |
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Affiliation: | Oncology iMed, AstraZeneca, Centre de Recherches, Z.I. la Pompelle, BP1050, 51689 Reims Cedex 2, France |
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Abstract: | The synthesis of differentially-substituted 3,5-bis(arylamino)pyrazoles has not yet been documented. During our investigation, we managed to develop a novel, entirely combinatorial synthesis of 3,5-bis(arylamino)pyrazoles relying on a simple one-pot two-step operation. |
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