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Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi
Authors:Michelle S LiberioDhanya Sooraj  Elizabeth D WilliamsYunjiang Feng  Rohan A Davis
Institution:a Eskitis Institute, Griffith University, Brisbane, QLD 4111, Australia
b Centre for Cancer Research, Monash Institute of Medical Research, Monash University, VIC 3168, Australia
Abstract:Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinideskingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretation of 1D/2D NMR and MS data, and the absolute configuration was determined using Marfey’s method. This is the first report of a natural product from L. kingi.
Keywords:Kingamide A  Natural product  Alkaloid  Ascidian  Leptoclinides kingi
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