Solvent effects on amphotericin B monolayers |
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| Authors: | Sykora Jennifer Cannon Neely William C Vodyanoy Vitaly |
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| Affiliation: | Department of Chemistry, Auburn University, Auburn, AL 36849, USA. |
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| Abstract: | Monolayers of the antifungal antibiotic amphotericin B undergo the liquid expanded/liquid condensed state transition if spread from chloroform/methanol solvent. The transition disappeared after a long spreading time. The presence of the transition may be due to the retention of solvent and/or the presence of metastable aggregates of amphotericin B. |
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