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Recent Aspects of Pharmaceutical Application of Cyclodextrins
Authors:Kaneto Uekama
Abstract:Because of the multi-functional characteristics and bioadaptability, cyclodextrin (CyD) is capable of alleviating the undesirable properties of drug molecules through the formation of inclusion complexes. This paper outlines the current application of natural and chemically modified CyDs in the various pharmaceutical formulations including peptide and protein drugs. Furthermore, potential use of CyD/drug conjugates in site-specific drug delivery is discussed.
Keywords:controlled drug release  cyclodextrin derivative  drug carrier  pharmaceutical application  site-specific drug delivery
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