Isolation and structural elucidation of a novel rotenoid from the seeds of Clitoria fairchildiana |
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| Authors: | Mathias Leda Da Silva Bernadete Pereira Mors Walter Baptist Parente José Paz |
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| Institution: | Laboratório de Química de Plantas Medicinais, Núcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, PO Box 68045 CEP 21944-970 Rio de Janeiro, Brazil. |
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| Abstract: | The seeds of Clitoria fairchildiana provided a new rotenoid, 6-hydroxy-2,3,9-trimethoxy-1]benzopyrano3,4-b]1]benzopyran-12(6H)-one. The structural elucidation was performed using detailed analyses of H- and 13C-NMR spectra including 2DNMR spectroscopic techniques (1H-13CHETCOR) and by comparison with spectrometric data from the literature. The anti-inflammatory activity was investigated using a capillary permeability assay. |
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