Synthetic approaches to physiologically active polycyclic compounds: VII. Synthesis of 2-(7-Hydroxybicyclo-[3.3.1]non-3-ylmethyl)propane-1,3-diol |
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| Authors: | O N Zefirova E V Nurieva V N Nuriev A A Ivanov N V Zyk N S Zefirov |
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| Institution: | (1) Faculty of Chemistry, Moscow State University, Vorob’evy gory 1, Moscow, 119992, Russia;(2) Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow oblast, Russia |
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| Abstract: | 2-(endo-7-Hydroxybicyclo3.3.1]non-exo-3-ylmethyl)propane-1,3-diol was synthesized in seven steps starting from endo-7-hydroxybicyclo3.3.1]nonane-exo-3-carboxylic acid. The title compound attracts interest as intermediate product for the synthesis of potential tubulin ligands. |
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