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Synthesis of adenosine containing carborane modification |
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| Authors: | Agnieszka B. Olejniczak Andrey Semenuk Marek Kwiatkowski Zbigniew J. Lesnikowski |
| Affiliation: | a Laboratory of Molecular Virology and Biological Chemistry, Center for Microbiology and Virology PAS, 106 Lodowa St., Lodz 93-232, Poland b Institutionen för Genetik och Patologi, Rudbecklaboratoriet, Uppsala Universitet, Uppsala 751 85, Sweden |
| Abstract: | The carboranyl cage is a new modifying entity for nucleosides and DNA-oligonucleotides. Most of carborane–nucleoside conjugates described so far belong to pyrimidine series. Herein, the first synthesis of adenosine, nucleoside containing purine nucleic base, modified with carborane cluster, is described. |
| Keywords: | Boron Carborane Nucleosides Antiviral BNCT |
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