| Enzymatic Synthesis and Characterization of Novel Amphiphilic Triblock Copolymer Poly（p-dioxanoneco-5-benzyloxytrimethylene carbonate）-block-poly（ethylene glycol） |
| |
| 引用本文： | Hua Li JIA Feng HE Jun FENG Ren Xi ZHUO. Enzymatic Synthesis and Characterization of Novel Amphiphilic Triblock Copolymer Poly（p-dioxanoneco-5-benzyloxytrimethylene carbonate）-block-poly（ethylene glycol）[J]. 中国化学快报, 2006, 17(8): 1113-1116 |
| |
| 作者姓名： | Hua Li JIA Feng HE Jun FENG Ren Xi ZHUO |
| |
| 作者单位： | Hua Li JIA，Feng HE*，Jun FENG，Ren Xi ZHUO Key Laboratory of Biomedical Polymers of Ministry of Education，Department of Chemistry，Wuhan University，Wuhan 430072 |
| |
| 摘 要： | In recent years, amphiphilic block copolymers consisting of hydrophilic and hydrophobic segments have attracted much attention, because of their unique phase behavior in aqueous media and potential applications as drug delivery systems1. Poly(ethylene gly…
|
| 关 键 词： | 两性共聚物 聚乙二醇 5-苄氧基三亚甲基碳酸酯 p-二氧酮 酶聚合反应 |
| 收稿时间： | 2006-01-19 |
Enzymatic Synthesis and Characterization of Novel Amphiphilic Triblock Copolymer Poly(p-dioxanone-co-5-benzyloxytrimethylene carbonate)-block-poly(ethylene glycol) |
| |
| Hua Li JIA,Feng HE,Jun FENG,Ren Xi ZHUO. Enzymatic Synthesis and Characterization of Novel Amphiphilic Triblock Copolymer Poly(p-dioxanone-co-5-benzyloxytrimethylene carbonate)-block-poly(ethylene glycol)[J]. Chinese Chemical Letters, 2006, 17(8): 1113-1116 |
| |
| Authors: | Hua Li JIA Feng HE Jun FENG Ren Xi ZHUO |
| |
| Abstract: | Novel amphiphilic triblock copolymer poly(p-dioxanone-co-5-benzyloxytrimethylene carbonate)-block-poly(ethylene glycol)-block-poly(p-dioxanone-co-5-benzyloxytrimethylene car- bonate) (p(PDO-co-BTMC)-b-PEG-b-p(PDO-co-BTMC)) was successfully synthesized using immobilized porcine pancreas lipase on porous silica particles (IPPL) as the catalyst for the first time. 1H NMR, 13C NMR and GPC analysis were used to confirm the structures of resulting copolymers. The molecular weight (Mn) of the copolymer with feed ratio of 69:20:11 (BTMC: PDO: PEG ) was 31300 g/mol and the polydispersity was 1.85, while the Mn decreased to 25000 g/mol and polydispersity of 1.93 with the feed ratio of 50:40:10. |
| |
| Keywords: | Amphiphilic copolymer poly(ethylene glycol) 5-benzyloxytrimethylene carbonate p-dioxanone enzymatic polymerization. |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
