Sterostreins A-E, new terpenoids from cultures of the Basidiomycete Stereum ostrea BCC 22955 |
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| Authors: | Isaka Masahiko Srisanoh Urarat Choowong Wilunda Boonpratuang Thitiya |
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| Affiliation: | National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand. isaka@biotec.or.th |
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| Abstract: | Sterostreins A-E (1, 2, 3a/3b, 4, and 5), five novel terpenoids, were isolated from cultures of the mushroom fungus Stereum ostrea BCC 22955. Sterostrein A (1) exhibited antimalarial activity (IC(50) 2.3 μg/mL) and cytotoxicity (IC(50) 5.3-38 μg/mL). |
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