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Microbial Transformation of Taxoids and Synthesis of Taxoids ith an Oxetane Ring
引用本文:Shang Hut HU, Xu Fang TIAN, Wen Yi HE, Man KONG, Di An SUN,Qi Cheng FANG(Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050). Microbial Transformation of Taxoids and Synthesis of Taxoids ith an Oxetane Ring[J]. 中国化学快报, 1998, 0(1)
作者姓名:Shang Hut HU   Xu Fang TIAN   Wen Yi HE   Man KONG   Di An SUN  Qi Cheng FANG(Institute of Materia Medica  Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing 100050)
作者单位:Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050
摘    要:SincethediscoveryofanhcanceragentPaclitaxel(Taxol@),'studiesonTaxUsSPecieshaVebroughtmorethantwohundrednewtaxoidsintothetaxanediterpenoidfaIYuly.'Recently,Zap-DeacetoxytaxinineJ1andsomeofitsanalogswereisolatedinhighamountsfromTaxusyUnnanensisandotherTaresspecies.2Itseemsthat1anditsanalogscanbeusedasstaltingmaterialsforthechemoenZylnaticSynthesisofpaclitaXelanalogs,aswellasvaluableforthestudyofthebiosynthesisoftaxoidsinToosspecies.MicrobialenZymaticSystemsmayserveasPOwerfultoolstOndnd…


Microbial Transformation of Taxoids and Synthesis of Taxoids with an Oxetane Ring
Shang Hut HU, Xu Fang TIAN, Wen Yi HE, Man KONG, Di An SUN,Qi Cheng FANG. Microbial Transformation of Taxoids and Synthesis of Taxoids with an Oxetane Ring[J]. Chinese Chemical Letters, 1998, 0(1)
Authors:Shang Hut HU   Xu Fang TIAN   Wen Yi HE   Man KONG   Di An SUN  Qi Cheng FANG
Abstract:
Keywords:Taxoid   abeotaxane   oxetane ring   chemoenzymatic method
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