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Application of partial least square on quantitative analysis of L-, D-, and DL-tartaric acid by terahertz absorption spectra
Authors:Nishikiori Rika  Yamaguchi Mariko  Takano Keisuke  Enatsu Tokujiro  Tani Masahiko  de Silva U Chandimal  Kawashita Norihito  Takagi Tatsuya  Morimoto Shotaro  Hangyo Masanori  Kawase Masaya
Institution:Faculty of Pharmaceutical Sciences, Osaka Ohtani University, 3-11-1 Nishikiori-kita, Tondabayashi, Osaka 584-8540, Japan.
Abstract:Absorption spectra of polycrystalline L-, D-, and DL-tartaric acid have been measured by terahertz time domain spectroscopy (THz-TDS). Different absorption bands are observed for DL-tartaric acid and its enantiomers (L- and D-tartaric acid). This result shows that the THz-TDS can be used for distinguishing between DL-tartaric acid and enantiomers (L- and D-tartaric acid). Moreover, partial least square (PLS) can be found to improve the quantitation of L-tartaric acid in L- and DL-tartaric acid mixture by THz-TDS.
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