Multicomponent Synthesis of 2,5-Dioxo- and 4-Aryl-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinazolines |
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| Authors: | N. N. Tonkikh A. Strakovs M. V. Petrova |
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| Affiliation: | (1) Riga Technical University, Riga LV-1048, Latvia |
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| Abstract: | Ten 2,5-dioxo- and 4-aryl-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinazolines have been synthesized in three-component interactions of 1,3-cyclohexanedione or dimedone, urea or thiourea, and substituted benzaldehydes (3-bromo-, 4-bromo-, 4-fluoro-, 4-methoxy-, 3,4-methylenedioxy-, and 3-nitro-). 9-Aryl-4,5-dioxo-1,2,3,4,5,6,7,8-octahydro-9H-xanthenes were also formed in these reactions. |
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| Keywords: | 2,5-dioxo- and 5-oxo-2-thioxo-4-aryl-1,2,3,4,5,6,7,8-octahydroquinazolines substituted benzaldehydes ureas 1,3-cyclohexanediones three-component synthesis |
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