Self-assembly of cyclic homo- and hetero-beta-peptides with cis- furanoid sugar amino acid and beta-hGly as building blocks |
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Authors: | Jagannadh Bulusu Reddy Marepally Srinivasa Rao Chennamaneni Lohitha Prabhakar Anabathula Jagadeesh Bharatam Chandrasekhar Srivari |
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Institution: | Indian Institute of Chemical Technology, Hyderabad-7, India. jagan@iict.res.in |
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Abstract: | The design, synthesis and characterization of a new class of peptide nanotubes, self-assembled from cyclic homo- and hetero-beta-peptides based on cis-furanoid sugar amino acid and beta-hGly residues are described; these results represent the expansion of the conformational pool of cis beta-sugar amino acids in the design of peptide nanotubes. |
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