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In vitro effects of ultra-low and low doses of radiation produced by sources of different nature and power on enzymes
Authors:M. A. Orlova  O. A. Kost  V. A. Gribkov  A. V. Dubrovsky  P. V. Binevsky  I. I. Nikolskaya  S. E. Ulianenko  A. A. Poloznikov  A. P. Orlov
Affiliation:1. Department of Chemistry, M. V. Lomonosov Moscow State University, 1 Leninskie Gory, 117234, Moscow, Russian Federation
2. D. Rogachev Federal Scientific Clinical Centre of Pediatric Hematology, Oncology and Immunology, 117 Build 2 Leninskii prosp., 117997, Moscow, Russian Federation
3. A. A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, 49 Leninskii prosp., 119991, Moscow, Russian Federation
4. Medical Radiological Research Center, Ministry of Health of the Russian Federation, 4 ul. Koroleva, 249036, Obninsk, Russian Federation
Abstract:The effects of low and ultra-low doses of X-ray radiation and neutron fluxes produced by continuous-wave and pulsed sources of different nature and power on the activity of plant peroxidases and the bovine lung angiotensin-converting enzyme were studied. Certain ranges of doses (including ultra-low), the exposure to which under particular conditions causes the in vitro activation and/or inactivation of the enzymes, were found. Possible factors responsible for this phenomenon are discussed.
Keywords:
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