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Chemical constituents of Ligularia virgaurea and its diversity in southwestern Sichuan of China |
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| Authors: | Motoo Tori Kaori Honda Yasuko Okamoto Shigeru Takaoka Yuemao Shen Ryo Hanai |
| Institution: | a Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, 770-8514, Japan b Kunming Institute of Botany, Chinese Academy of Science, Kunming 654204, China c Department of Chemistry, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan d Department of Life Science, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan |
| Abstract: | Chemical constituents of root extract and the nucleotide sequences of the atpB-rbcL intergenic region and the internal transcribed spacers (ITSs) of the ribosomal RNA gene were studied for Ligularia virgaurea var. virgaurea collected in southwestern Sichuan Province of China. Eleven samples were collected. Four of them were found to contain four new furanoeremophilanes, virgaurenones A-D, as well as a new eremophilanolide, virgaurenolide A. The other samples contained different furanoeremophilanes and their derivatives including nor-type of compounds, two of which were new. Diversity was found to be present in the nucleotide sequences as well. The chemical composition was found to be correlated with the ITS variation but not with the geographic distribution of the samples. |
| Keywords: | Ligularia virgaurea Sesquiterpene Furanoeremophilane atpB-rbcL ITS Diversity |
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