Synthesis of (<Emphasis Type="Italic">S</Emphasis>)-(-)-1,4-diaryl-6-methyl-4-trifluoromethyl-3,4-dihydropyrimidine-2(1<Emphasis Type="Italic">H</Emphasis>)-thiones |
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| Authors: | N M Golovach V A Sukach M V Vovk |
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| Institution: | 1.Institute of Organic Chemistry,National Academy of Sciences of Ukraine,Kiev,Ukraine |
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| Abstract: | (S)-(+)-4-Amino-4-aryl-5,5,5-trifluoropentan-2-one reacted with aryl isothiocyanates containing electron-withdrawing substituents
to give (S)-(−)-1,4-diaryl-6-methyl-4-trifluoromethyl-3,4-dihydropyrimidine-2(1H)-thiones. |
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