Natural dissolved organic matter affects electrospray ionization during analysis of emerging contaminants by mass spectrometry |
| |
Authors: | Samanthi Wickramasekara,Selene Herná ndez-Ruiz,Leif Abrell,Robert Arnold,Jon Chorover |
| |
Affiliation: | 1. Department of Soil, Water and Environmental Science, University of Arizona, Tucson, AZ 85721, USA;2. Department of Chemical and Environmental Engineering, University of Arizona, Tucson, AZ 85721, USA;3. Arizona Laboratory for Emerging Contaminants, University of Arizona, Tucson, AZ 85721, USA |
| |
Abstract: | Dissolved organic matter (DOM), present in many forms in water, can interfere with analysis of organic contaminants by atmospheric pressure ionization–mass spectrometry. A quantitative analysis of this interference, or matrix effect, on organic contaminant target analyte measurements was carried out using un-fractionated and fractionated dissolved natural organic matter from the Suwannee River, GA (SROM), a standard reference material, that was directly infused into the tandem mass spectrometer during multiple reaction monitoring (MRM) of a suite of endocrine disrupting compounds–pharmaceuticals and personal care products (EDC/PPCPs). Most target analytes suffered signal suppression in the presence of both fractionated and un-fractionated SROM, however greater interferences were measured with fractionated relative to bulk SROM. This finding is consistent with the view of organic matter as a supramolecular association of low molecular mass components having separate charged and structural features revealed only after dissociation. |
| |
Keywords: | SROM, Suwannee River organic matter DOM, dissolved organic matter DOC, dissolved organic carbon HoA, hydrophobic acid HoB, hydrophobic base HoN, hydrophobic neutral HiA, hydrophilic acid HiB, hydrophilic base HiN, hydrophilic neutral |
本文献已被 ScienceDirect 等数据库收录! |
|