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The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex
Authors:Dr Nicola Salvi  Dr Evangelos Papadopoulos  Dr Martin Blackledge  Prof Gerhard Wagner
Institution:1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA;2. Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
Abstract:
Keywords:allosterism  inhibitors  molecular dynamics  NMR spectroscopy  protein–  protein interactions
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