Palladium(II)‐Catalyzed Tandem Synthesis of Acenes Using Carboxylic Acids as Traceless Directing Groups |
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| Authors: | Kiho Kim Dr Dhananjayan Vasu Honggu Im Prof Dr Sungwoo Hong |
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| Institution: | 1. Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, Korea;2. Center for Catalytic Hydrocarbon Functionalization Institute for Basic Science (IBS), Daejeon, Korea |
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| Abstract: | A straightforward synthetic strategy for generating useful anthracene derivatives was developed involving palladium(II)‐catalyzed tandem transformation with carboxylic acids as traceless directing groups. Carboxyl‐directed C‐H alkenylation, carboxyl‐directed secondary C‐H activation and rollover, intramolecular C?C bond formation, and decarboxylative aromatization are proposed as the key steps in the tandem reaction pathway. This novel synthetic route utilizes a broad range of substrates and provides a convenient synthetic tool that allows access to acenes. |
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| Keywords: | acenes C-H functionalization decarboxylation palladium tandem reactions |
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