Guaianolides from Salvia nubicola (Lamiaceae) |
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| Authors: | Ali Muhammad Shaiq Ahmed Waqar Armstrong Andrea Florence Ibrahim Syed Amir Ahmed Shakeel Parvez Masood |
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| Affiliation: | H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, Pakistan. shaiq303@hotmail.com |
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| Abstract: | A new sesquiterpene-lactone (nubenolide) belonging to the guaianolide class along with its acetate (nubenolide acetate) and a dimer (bisnubenolide) have been isolated from Salvia nubicola collected from Quetta, Pakistan. Structures of all three new metabolites were elucidated with the aid of spectroscopic techniques including 2D-NMR. However, the structure of nubenolide was finally confirmed via single-crystal X-ray diffraction method. |
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