A [3 + 3] annelation approach to tetrahydropyridines |
| |
| Authors: | Pattenden Lisa C Wybrow Robert A J Smith Stephen A Harrity Joseph P A |
| |
| Institution: | Department of Chemistry, University of Sheffield, Brook Hill, UK. |
| |
| Abstract: | reaction: see text] A stepwise 3+3] annelation sequence to tetrahydropyridines via addition of the Büchi Grignard to aziridines has been developed. These intermediates can be further functionalized with good regio- and stereocontrol and this methodology has been employed in the stereoselective formal synthesis of (-)-dihydropinidine. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
