Quantitative Single-Ion Irradiation by ASIPP Microbeam |
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作者姓名: | 王旭飞 陈连运 胡智文 王晓华 张俊 李军 陈斌 胡素华 时钟涛 吴瑜 许明亮 吴李君 王绍虎 余增亮 |
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作者单位: | KeyLaboratoryofIonBeamBioengineering,ChineseAcademyofSciences,Hefei230031 |
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摘 要: | A single-ion microbeam facility has been constructed by the microbeam research group in ASIPP (Institute of Plasma Physics, Chinese Academy of Science). The system was designed to deliver defined numbers of hydrogen ions produced by a van de Graaff accelerator, covering an energy range from 200 keV to 3 MeV, into living cells (5μm-20μm diameter) growing in culture on thin plastic films. The beam is collimated by a 1-μm inner diameter HPLC (high performance liquid chromatograph) capillary, which forms the micron-dimensional beam-line exit. A microbeam collimator, a scintillation ion counting system and a fast beam shutter, which constitute a precise dosage measuring and controlling system, jointly perform quantitative single-ion irradiation. With this facility, we can presently acquire ion-hitting efficiency close to 95%.
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关 键 词: | 定量单离子照射 ASIPP微束 Graaff加速器 辐射生物学 癌症治疗 |
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