Poly-aminoalkylation d'amines,en solution aqueuse ou aquo-alcoolique, à l'aide d'acides amino-2-alkylsulfuriques

Alkali stable primary and secondary amines (of the types H₂NCH₂CH₂OPO₃Na₂, H₂NCH₂COONa, H₂NCH₂CH₂OH, H₃CNHCH₂CH₂OH, etc.) heated with n mole-equiv. of a 2-amino-1-alkylsulfuric acid in aqueous solution, in the presence of 2 n mole-equiv. of NaOH, giverise to a mixture of poly-aminoalkylated derivatives with an average degree of aminoalkylation close to n. If the amine is insoluble in water, a mixture of water+an alcohol can be used. In the case of N-methylaminoethylsulfuric acid, the reaction is carried out in a closed vessel since the intermediate N-methylaziridine boils at 27,5° under normal pressure. These polyaminoalkyl derivatives are capable of being acylated, alkylated, and cyclized. Some stearylated products are described.