Simultaneous spectrophotometric determination of cobalt and nickel by partial least square regression in micellar media

Diphenycarbazone has been used for the simultaneous determination of cobalt and nickel by partial least square regression method. DPC complexes of cobalt and nickel at pH 7-10 are of pink color, which are soluble in TX-100 micellar media. A partial least square multivariate calibration method for the analysis of binary mixtures of cobalt and nickel was developed. The total relative standard error for applying the PLS method was calculated. The accuracy and reproducibility of the determination method for various known amounts of Co(II) and Ni(II) in their binary mixtures were tested. The effects of diverse ions on the determination of cobalt and nickel to investigate the selectivity of the method were also studied. The proposed method was applied to the synthetic binary mixtures, alloys and pharmaceutical samples.