An Analysis of Drug Dissolution Rates in the USP 24 Type 2 Apparatus |
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| Authors: | David McDonnell Brendan Redmond Deirdre M D'Arcy Anne Marie Healy Owen I Corrigan |
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| Institution: | 1. School of Mathematical Sciences, Dublin Institute of Technology, Kevin St, Dublin 8, Ireland;2. School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, Ireland |
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| Abstract: | This paper applies boundary layer theory to the process of drug dissolution in the USP 24, Type 2 Apparatus. The mass transfer rate from the top flat surface of a compact in various positions within the device is evaluated by means of a Pohlhausen integral method. (© 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim) |
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