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Synthesis of 1-(2-Ethoxyethyl)-4-hydroxy-4-[2-(1-hydroxycyclohexyl)ethynyl]piperidine and Heterocyclization under the Conditions of Hydration |
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| Authors: | K B Bazhykova I A Poplavskaya K D Praliev |
| Institution: | (1) A. B. Bekturov Institute of Chemical Sciences, Ministry of Education and Science, Republic of Kazakhstan, Almaty |
| Abstract: | The reaction of 1-(2-ethoxyethyl)piperidin-4-one with ethynylcyclohexanol led to the synthesis of a glycol, the hydration of which gave a mixture of spirocyclic compounds with a carbonyl group at various positions in the furan ring. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1649–1652, November, 2005. |
| Keywords: | 1-ethynyl-1-hydroxycyclohexane 3-(2′ -ethoxyethyl)-14(15)-oxo-7-oxa-3-azadispiro[5 1 5 2]pentadecane 1-(2-ethoxyethyl)piperidin-4-one hydration Favorsky reaction |
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