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An unexpected result in the condensation of 2-amino-6-bromopyridine with ethyl 4-chloroacetoacetate: Four dihalo-substituted pyrido[1,2-a]pyrimidin-4-ones as reaction products |
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| Authors: | Pier Luigi Ferrarini Claudio Mori Filippo Mori Giuseppe Saccomanni Silvia Barontini Marco Macchia Pier Luigi Barili Mahmoud Hamdan |
| Abstract: | We report here the condensation of 2-amino-6-bromopyridine with ethyl 4-chloroacetoacetate in polyphosphoric acid. In this reaction, a mixture of the four possible dihalo-4H-pyrido1,2-a]pyrimidin-4-ones 1–4 was obtained. |
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