A new scaffold for dipeptide β-turn mimetics: Expeditious synthesis of an unsaturated 6,5-fused bicyclic lactam |
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| Authors: | R gis Millet,Raymond Houssin,Jean-Pierre H nichart,Benoî t Rigo |
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| Affiliation: | Régis Millet,Raymond Houssin,Jean-Pierre Hénichart,Benoît Rigo |
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| Abstract: | Reported here is an easy and short synthesis of 6-acetamido-5-oxo-1,2,3,5,6,7-hexahydro-3-indolizine-carboxylic acid, originating from β-enaminoesters derived from pyroglutamic acid. This key compound has been used as a scaffold in the synthesis of dipeptido mimetics. |
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