A convenient method for the synthesis of six-membered heterocyclic enaminones |
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| Authors: | Pilar Puebla Zoila Honores Manuel Medarde Esther Caballero Arturo San Feliciano Lourdes Morn |
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| Institution: | Pilar Puebla,Zoila Honores,Manuel Medarde,Esther Caballero,Arturo San Feliciano,Lourdes Morán |
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| Abstract: | Enaminones are widely employed in the synthesis of heterocycles, however heterocyclic enaminones and their use in the synthesis of more complex systems have been less studied. The reaction between 4-chloroacetylacetate and aliphatic or aromatic 1,2-aminoalcohols, 1,2-aminothiols or 1,2-diamines, yields in one pot a six-membered 1,4-heterocyclic system containing the enaminone moiety. |
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