Improved chemical synthesis of UDP-galactofuranose |
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| Authors: | Marlow A L Kiessling L L |
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| Affiliation: | Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. |
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| Abstract: | [reaction: see text] A reliable and efficient synthetic route to UDP-alpha-D-galactofuranose (UDP-Galf) has been developed. Reaction of UMP-N-methylimidazolide with Galf 1-phosphate proceeds rapidly to provide UDP-Galf with excellent reproducibility and in a yield approximately twice as high as those reported previously. |
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