| BORONIC ACIDS AS LIGANDS FOR AFFINITY CHROMATOGRAPHY |
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| 引用本文： | 刘晓川. BORONIC ACIDS AS LIGANDS FOR AFFINITY CHROMATOGRAPHY[J]. 色谱, 2006, 24(1): 73-80 |
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| 作者姓名： | 刘晓川 |
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| 作者单位： | Department of Chemistry, California State Polytechnic University, Pomona, CA 91768, USA |
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| 摘 要： | A review on the principles and applications of boronic acids as affinity ligands for the chromatographic separation of carbohydrates, nucleic acid components, glycoproteins, and other small biomolecules. The mechanisms of interactions between boronate ligands and analytes are described. Various boronate ligands and supports are discussed. Examples of the use of boronate affinity chromatography for separation of each class of analytes are presented.
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| 关 键 词： | boronic acids borate boronate boronate affinity chromatography separation of glycoproteins |
| 文章编号： | 1000-8713（2006）01-0073-08 |
| 收稿时间： | 2005-12-31 |
| 修稿时间： | 2005-12-31 |
BORONIC ACIDS AS LIGANDS FOR AFFINITY CHROMATOGRAPHY |
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| LIU Xiao-Chuan. BORONIC ACIDS AS LIGANDS FOR AFFINITY CHROMATOGRAPHY[J]. Chinese journal of chromatography, 2006, 24(1): 73-80 |
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| Authors: | LIU Xiao-Chuan |
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| Affiliation: | Department of Chemistry, California State Polytechnic University, Pomona, CA 91768, USA |
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| Abstract: | A review on the principles and applications of boronic acids as affinity ligands for the chromatographic separation of carbohydrates, nucleic acid components, glycoproteins, and other small biomolecules. The mechanisms of interactions between boronate ligands and analytes are described. Various boronate ligands and supports are discussed. Examples of the use of boronate affinity chromatography for separation of each class of analytes are presented. |
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| Keywords: | boronic acids borate boronate boronate affinity chromatography separation of glycoproteins |
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