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The Synthesis of Some Novel N-[α-(Isoflavone-7-O-) Acetyl]Amino Acid Derivatives

作者姓名：	Peng LIU Jun Biao CHANG Rong Feng CHEN Qiang WANG Jing Xi XIE

作者单位：	Henan Institute of Chemistry，Henan Academy of Science，Zhengzhou 450002 Institute of Materia Medica，Chinese Academy of Medical Sciences and Peking Union Medical College，Beijing 100050

摘要：	IsoflavonoidsarebiologicallyimportantnaturalproductsoccurringmainlyinspeciesoftheLeguminosaefamilyandhaveshownawidespectrumofbiologicalactivitiesincludingestrogenic,anticancer,insecticidal,pisciadalandantifungalproperty'.Theseisoflavonoidphytoestrogensarerichinsomeplantdietsuchassoybean'.Animalexperimentshadshownthatsoybeandietinhibitradiation-andchemical-inducedtumorofthemammary',skin',andlivers.AstudyconductedbyBarnesetal.6suggestedthatsoybeanisoflavonesmayberesponsiblefortheanticarcinogeni…
关键词：	Isoflavone analogues N-[α-(isoflavone-7-O-)acetyl] amino acid methyl ester synthesis.
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