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Modification of biologically active amides and amines with fluorine-containing heterocycles 3*. Piracetam in the three-component reaction with methyl trifluoropyruvate and 1,3-binucleophiles |
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| Authors: | Sokolov V B Aksinenko A Yu Epishina T A Goreva T V Martynov I V |
| Institution: | 1.Institute of Physiologically Active Substances, Russian Academy of Sciences, 1 Severnyi proezd, Chernogolovka, 142432, Moscow Region, Russian Federation ; |
| Abstract: | Three-component reaction of Piracetam, methyl trifluoropyruvate and 1,3-binucleophiles, such as 6-aminouracils, 6-aminothiouracils, 4-(4-tolylamino)pent-3-en-2-one and N-substituted ureas, has been studied. This reaction resulted in fluorinated heterocyclic derivatives of Piracetam. |
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