|
|||||
|
|
Fluorine-containing quinazolines annulated at the pyrimidine ring |
|
| Authors: | Nosova E. V. Laeva A. A. Trashakhova T. V. Lipunova G. N. Slepukhin P. A. Charushin V. N. |
| Affiliation: | 1.Ural State Technical University — UPI, 19 ul. Mira, 620002, Ekaterinburg, Russian Federation ;2.I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22/20 ul. S. Kovalevskoi, 620041, Ekaterinburg, Russian Federation ; |
| Abstract: | Fluorine-containing quinazolines annulated at the sides [a] and [c] were synthesized by the reaction of 2- and 4-hydrazino-substituted quinazolines with aldehydes and subsequent oxidative cyclization. Annulation at the side [b] was performed by alkylation of 2-alkylthio-4(3H)-quinazolinones with bromoethanol and ipso-substitution of the alkylthio group. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |