High Sensitive Voltammetric Gentamicin Sensor using Poly (3-thiophenecarboxylic acid-co-3-methylthiophene) Modified Glassy Carbon Electrode

For the determination of gentamicin in biomedical applications, sensitive, fast and low cost voltammetric sensor has been developed. Prepared sensor was successfully used for determination of gentamicine in synthetic urine samples with different voltammetric measurement methods. Firstly, glassy carbon electrode was modified using cyclic voltammetry technique by electropolymerization of 3-thiophenecarboxylic acid and 3-methylthiophene. Then, optimization of the electrochemical parameters was carried out for modified electrode. With this modified electrode, gentamicin determination was performed in the linear range of 0.05–4.00 mM. The correlation coefficient, limit of detection and limit of quantitation were calculated as 0.9999, 0.039 mM and 0.129 mM, respectively.