Electrochemiluminescence Enhanced by the Synergetic Effect of Porphyrin and Multi-walled Carbon Nanotubes for Uric Acid Detection |
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Authors: | Liying Zhang Chuanrui Zhao Yujiao Bai Qian Wang Pan Ma Xiaojie Ma Peihua Zhu |
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Affiliation: | 1. School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022 P.R. China;2. Jinan Academy of Agricultural Sciences, Jinan, 250316 P.R. China;3. Qilu Hospital of Shandong University, Jinan, 250012 P.R. China |
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Abstract: | The design and exploration of efficient, stable and environmentally compatible organic emitters for an electrochemiluminescence (ECL) sensor is a promising topic. Herein, a novel environmentally-friendly luminophore, ZnBCBTP@MWCNTs, were fabricated via self-assembly of porphyrin molecules (ZnBCBTP) onto multi-walled carbon nanotubes (MWCNTs). The resulting luminophore ZnBCBTP@MWCNTs displayed not only the highly ECL property and but also the good accelerated electron mobility. Then, a label-free ECL biosensor based ZnBCBTP@MWCNTs was constructed for the ultrasensitive detection of uric acid. Excitingly, this proposed ECL biosensor performed a good linear relationship in the range of 0–300 μM with a low detection limit of 1.4 μM, thus offering another reliable and feasible sensing platform for clinical bioanalysis with good selectivity, stability, and repeatability. |
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Keywords: | Electrochemiluminescence Multi-walled carbon nanotubes Porphyrin Uric acid |
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