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Nonenzymatic Electrochemical Sensor for Wearable Interstitial Fluid Glucose Monitoring
Authors:Dr Lanjie Lei  Prof Chao Zhao  Dr Xiaofei Zhu  Mr Shuai Yuan  Dr Xing Dong  Dr Yinxiu Zuo  Prof Hong Liu
Institution:1. State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096 China

Lanjie Lei and Chao Zhao contributed equally to this work.;2. State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096 China

Abstract:We report on a nonenzymatic electrochemical sensor for wearable glucose monitoring in interstitial fluid. The sensor exhibited acceptable selectivity and reliability for continuous glucose detection for up to 30 days. The sensor tip is coated with polyurethane, and the biocompatibility of the tip is investigated by tissue staining. A fully integrated wearable glucose monitoring system is developed with a wireless connection with a smartphone. The test results are in agreement with reference methods. So, we believe the sensor is promising for the development of a continuous glucose monitoring system and diabetes management.
Keywords:Nonenzymatic  Sensor  Interstitial Fluid  Glucose  Diabetes
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